Traditional medicinal applications are related to digestion and nervous discomfort. Lemon verbena ( Aloysia citriodora (L.)) is an annual eatable herbaceous plant native to South America commonly used as tea, refreshing beverage, food, or spice. Many of these ingredients and products have been investigated in recent years for example, curcumin, omega-3 fatty acids and polyphenols. The use of supplements with antioxidative or anti-inflammatory effects in the sports nutrition is already widespread. As inflammation and ROS (reactive oxygen species) are presumably the main cause of DOMS, it is hypothesized that natural ingredients with anti-inflammatory and antioxidative properties may help in accelerating or supporting the regeneration after muscle damage inducing exercise. Therefore, it is important for the adherence to training plans and for the training success that regeneration is as effective and as short as possible.Ī product that could accelerate recovery from DOMS or muscular fatigue would be beneficial not only for high performance athletes, but also for amateur athletes, enabling them to train more frequently or reduce the risk of injury. Incomplete regeneration of myofibrillar structures and metabolic processes before the next training increases the risk for secondary injuries. DOMS is associated with muscle fatigue and muscle soreness, symptoms, which last for a number of days and have a negative impact on the exercise performance of athletes and amateur sports people, especially when they carry out long-term training programs. Delayed onset muscle soreness (DOMS) is the most common symptom of eiMD, whereas histological evidence of disruption of the myofibrillar structure and myofibre necrosis, as well as inflammation, are the ultimate signs of eiMD. Registered 28 September 2016Īll kinds of training, moderate, exhaustive or unaccustomed, cause so-called exercise-induced muscle damage (eiMD) accompanied by oxidative stress and inflammation.
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The trial was registered in the clinical trials registry (clinical NCT02923102). Lemon verbena extract (Recoverben®) has been shown to be a safe and well-tolerated natural sports ingredient, by reducing muscle damage after exhaustive exercise.
Creatine kinase and IL-6 didn’t show significant discrimmination between groups. Compared to placebo, lemon verbena extract receiving participants had significantly less exercise-related loss of muscle strength ( p = 0.0311) over all timepoints, improved glutathione peroxidase activity by trend ( p = 0.0681) and less movement induced pain ( p = 0.0788) by trend.
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Participants in the lemon verbena group benefited from less muscle damage as well as faster and full recovery. Muscle strength (MVC), muscle damage (CK), oxidative stress (GPx), inflammation (IL6) and volunteer-reported muscle soreness intensity were assessed pre and post exercise. The 15 days intervention was divided into 10 days supplementation prior to the exhaustive exercise day (intensive jump-protocol), one day during the test and four days after.
Forty-four healthy males and females, which were 22–50 years old and active in sports, were randomized to 400 mg lemon verbena extract once daily or placebo. The study was performed as a randomized, placebo-controlled, double-blind study with parallel design. The aim of this study was to investigate the effects of a proprietary lemon verbena extract (Recoverben®) on muscle strength and recovery after exhaustive exercise in comparison to a placebo product. Lemon verbena leaves, commonly used as tea and refreshing beverage, demonstrated antioxidant and anti-inflammatory properties.
Exhaustive exercise causes muscle damage accompanied by oxidative stress and inflammation leading to muscle fatigue and muscle soreness.
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